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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CD33 All Species: 5.15
Human Site: S248 Identified Species: 22.67
UniProt: P20138 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P20138 NP_001763.3 364 39825 S248 G I F P G D G S G K Q E T R A
Chimpanzee Pan troglodytes Q64JA4 387 42507 T247 T V F Q G D G T A S T T L R N
Rhesus Macaque Macaca mulatta XP_001114616 415 45504 L299 N P R T D I F L G D G S G K Q
Dog Lupus familis XP_541460 697 77324 T395 S I F Q R E G T G T E A L G N
Cat Felis silvestris
Mouse Mus musculus Q63994 403 44806 E248 L V L V A V G E A T V K L L I
Rat Rattus norvegicus P07722 626 69334 S247 P V I V E M N S S V E A I E G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 48 76.3 31.5 N.A. 40.9 20.9 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 59.9 79.2 40.3 N.A. 52.3 32.1 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 33.3 6.6 26.6 N.A. 6.6 6.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 46.6 13.3 46.6 N.A. 20 20 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 17 0 0 0 34 0 0 34 0 0 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 17 34 0 0 0 17 0 0 0 0 0 % D
% Glu: 0 0 0 0 17 17 0 17 0 0 34 17 0 17 0 % E
% Phe: 0 0 50 0 0 0 17 0 0 0 0 0 0 0 0 % F
% Gly: 17 0 0 0 34 0 67 0 50 0 17 0 17 17 17 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 34 17 0 0 17 0 0 0 0 0 0 17 0 17 % I
% Lys: 0 0 0 0 0 0 0 0 0 17 0 17 0 17 0 % K
% Leu: 17 0 17 0 0 0 0 17 0 0 0 0 50 17 0 % L
% Met: 0 0 0 0 0 17 0 0 0 0 0 0 0 0 0 % M
% Asn: 17 0 0 0 0 0 17 0 0 0 0 0 0 0 34 % N
% Pro: 17 17 0 17 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 34 0 0 0 0 0 0 17 0 0 0 17 % Q
% Arg: 0 0 17 0 17 0 0 0 0 0 0 0 0 34 0 % R
% Ser: 17 0 0 0 0 0 0 34 17 17 0 17 0 0 0 % S
% Thr: 17 0 0 17 0 0 0 34 0 34 17 17 17 0 0 % T
% Val: 0 50 0 34 0 17 0 0 0 17 17 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _